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Tamai, Hiroshi; Mochiji, Toshiro; Senzaki, Masao*; Iwamoto, Tomonori*; Ishiguro, Yuzuru*; Kitade, Yuta; Sato, Heigo*; Suehiro, Rie*; Taniguchi, Tomihiro*; Fukasawa, Tetsuo*; et al.
Dai-41-Kai Nihon Kaku Busshitsu Kanri Gakkai Nenji Taikai Kaigi Rombunshu (Internet), 4 Pages, 2020/11
In light of recent delay of plutonium use in Japan and the increasing criticism of nuclear non-proliferation and nuclear security in the nuclear fuel cycle, the validity of these criticisms will be examined for the sustainable development of the nuclear fuel cycle policy. Issues on the view point of nuclear non-proliferation and nuclear security are examined.
by ion beam breeding technologySato, Katsuya; Ueda, Ryoshiro*; Hase, Yoshihiro; Narumi, Issey*; Ono, Yutaka
JAEA-Review 2015-022, JAEA Takasaki Annual Report 2014, P. 100, 2016/02
Ueda, Ryoshiro*; Sato, Katsuya; Hayashi, Hidenori*; Narumi, Issey*; Ono, Yutaka
JAEA-Review 2015-022, JAEA Takasaki Annual Report 2014, P. 101, 2016/02
Ono, Yutaka; Hase, Yoshihiro; Sato, Katsuya; Nozawa, Shigeki; Narumi, Issey*
Hoshasen To Sangyo, (138), p.17 - 20, 2015/06
no abstracts in English
Sato, Katsuya; Ueda, Ryoshiro; Hase, Yoshihiro; Narumi, Issey*; Ono, Yutaka
JAEA-Review 2014-050, JAEA Takasaki Annual Report 2013, P. 117, 2015/03
Ueda, Ryoshiro; Sato, Katsuya; Hayashi, Hidenori*; Narumi, Issey*; Ono, Yutaka
JAEA-Review 2014-050, JAEA Takasaki Annual Report 2013, P. 118, 2015/03
geneOba, Hirofumi*; Sato, Katsuya*; Yanagisawa, Tadashi*; Narumi, Issei
Gene, 363, p.133 - 141, 2005/12
Times Cited Count：35 Percentile：55.59(Genetics & Heredity)Three transcriptional start points for the 
were located at positions -156, -154 and -22 upstream from the 
translation initiation site. The amount of the three extended products increased in cells exposed to 2-kGy followed by a 0.5-h post-incubation, suggesting the existence of at least two radiation responsive promoters for expression. A luciferase reporter assay revealed that the distal promoter is located between positions -208 and -156 from the translation initiation site, while the proximal promoter is located between positions -57 and -22. The region located between positions -57 and -38 was indispensable for proximal promoter activity. Site-directed mutagenesis of a thymine positioned at -33 resulted in severe impairment of promoter activity, and suggested that the thymine functions as a master base for the proximal radiation responsive promoter. The results also suggested that up-regulation of expression by the 
gene product is triggered at the promoter level.
, 
or 
gene product for UV resistance in Tanaka, Masashi*; Narumi, Issei; Funayama, Tomoo; Kikuchi, Masahiro; Watanabe, Hiroshi*; Matsunaga, Tsukasa*; Nikaido, Osamu*; Yamamoto, Kazuo*
Journal of Bacteriology, 187(11), p.3693 - 3697, 2005/06
Times Cited Count：47 Percentile：62.15(Microbiology)no abstracts in English
Kobayashi, Yasuhiko; Narumi, Issei; Sato, Katsuya; Funayama, Tomoo; Kikuchi, Masahiro; Kitayama, Shigeru; Watanabe, Hiroshi*
Uchu Seibutsu Kagaku, 18(3), p.134 - 135, 2004/11
no abstracts in English
that stimulates DNA ligationNarumi, Issei; Sato, Katsuya; Cui, S.*; Funayama, Tomoo; Kitayama, Shigeru; Watanabe, Hiroshi*
Molecular Microbiology, 54(1), p.278 - 285, 2004/10
Times Cited Count：133 Percentile：91.37(Biochemistry & Molecular Biology)The extraordinary radiation resistance of results from the efficient capacity of the bacterium to repair DNA double-strand breaks. By analyzing the DNA damage repair-deficient mutant, KH311, a unique radiation-inducible gene (designated ) responsible for loss of radiation resistance was identified. Investigations in vitro showed that the gene product of (PprA) preferentially bound to double-stranded DNA carrying strand breaks, inhibited 
exonuclease III activity, and stimulated the DNA end-joining reaction catalyzed by ATP-dependent and NAD-dependent DNA ligases. These results suggest that 
has a radiation-induced nonhomologous end-joining repair mechanism in which PprA plays a critical role.
Shimada, Michiya; Mukhovatov, V.*; Federici, G.*; Gribov, Y.*; Kukushkin, A.*; Murakami, Yoshiki*; Polevoi, A. R.*; Pustovitov, V. D.*; Sengoku, Seio; Sugihara, Masayoshi
Nuclear Fusion, 44(2), p.350 - 356, 2004/02
Recent performance analysis has improved confidence in achieving Q 
10 in inductive operation in ITER. Performance analysis based on empirical scaling shows the feasibility of achieving Q 10 in inductive operation with a sufficient margin. Theory-based core modeling indicates the need of high pedestal temperature (2-4 keV) to achieve Q 10, which is in the range of projection with pedestal scaling. The heat load of type-I ELM could be made tolerable by high density operation and further tilting the target plate (if necessary). Pellet injection from High-Field Side would be useful in enhancing Q and reducing ELM heat load. Steady state operation scenarios have been developed with modest requirement on confinement improvement and beta (HH98(y,2) 1.3 and betaN 2.6). Stabilisation of RWM, required in such regimes, is feasible with the present saddle coils and power supplies with double-wall structure taken into account.
Shimada, Michiya; Mukhovatov, V.*; Federici, G.*; Gribov, Y.*; Kukushkin, A. S.*; Murakami, Yoshiki*; Polevoi, A. R.*; Pustovitov, V. D.*; Sengoku, Seio; Sugihara, Masayoshi
Nuclear Fusion, 44(2), p.350 - 356, 2004/02
Times Cited Count：40 Percentile：75.59(Physics, Fluids & Plasmas)Performance analysis based on empirical scaling shows the feasibility of achieving Q 
10 in inductive operation. Analysis has also elucidated a possibility that ITER can potentially demonstrate Q 
50, enabling studies of self-heated plasmas. Theory-based core modeling indicates the need of high pedestal temperature (3.2 - 5.3 keV) to achieve Q 10, which is in the range of projection with presently available pedestal scalings. Pellet injection from high-field side would be useful in enhancing Q and reducing ELM heat load in high plasma current operation. If the ELM heat load is not acceptable, it could be made tolerable by further tilting the target plate. Steady state operation scenarios at Q = 5 have been developed with modest requirement on confinement improvement and beta (HH98(y,2) 1.3 and betaN 2.6). Stabilisation of RWM, required in such regimes, is feasible with the present saddle coils and power supplies with double-wall structure taken into account.
in the radioresistant bacterium Islam, M. S.*; Hua, Y.*; Oba, Hirofumi; Sato, Katsuya; Kikuchi, Masahiro; Yanagisawa, Tadashi*; Narumi, Issei
Genes and Genetic Systems, 78(5), p.319 - 327, 2003/10
Times Cited Count：14 Percentile：27.54(Biochemistry & Molecular Biology)no abstracts in English
Battista, J. R.*; Cox, M. M.*; Daly, M. J.*; Narumi, Issei; Radman, M.*; Sommer, S.*
Science, 302(24), p.567 - 568, 2003/10
no abstracts in English
Narumi, Issei
Hoshasen To Chikyu Kankyo; Seitaikei Eno Eikyo O Kangaeru, p.113 - 122, 2003/09
no abstracts in English
Narumi, Issei
Iden, 57(5), p.57 - 62, 2003/09
no abstracts in English
Narumi, Issei
Trends in Microbiology, 11(9), p.422 - 425, 2003/09
Times Cited Count：51 Percentile：89.95(Biochemistry & Molecular Biology)no abstracts in English
Hua, Y.*; Narumi, Issei; Gao, G.*; Tian, B.*; Sato, Katsuya; Kitayama, Shigeru; Shen, B.*
Biochemical and Biophysical Research Communications, 306(2), p.354 - 360, 2003/06
Times Cited Count：152 Percentile：95.76(Biochemistry & Molecular Biology)We have identified a unique deinococcal gene, , as a general switch for downstream DNA repair and protection pathways, from a natural mutant, in which is disrupted by a transposon. Complete functional disruption of the gene in wild-type leads to dramatic sensitivity to ionizing radiation. Radioresistance of the disruptant could be fully restored by complementation with . In response to radiation stress, PprI can significantly and specifically induce the gene expression of 
and and enhance the enzyme activities of catalases. These results strongly suggest that PprI plays a crucial role in regulating multiple DNA repair and protection pathways in response to radiation stress.
Narumi, Issei
Science & Technology Journal, 12(5), p.50 - 51, 2003/05
no abstracts in English
UV-endonuclease 
Kitayama, Shigeru; Narumi, Issei; Funayama, Tomoo; Watanabe, Hiroshi
Bioscience Biotechnology and Biochemistry, 67(3), p.613 - 616, 2003/03
Times Cited Count：3 Percentile：13.16(Biochemistry & Molecular Biology)no abstracts in English
